Кореспондиращ автор: С. Василев ( strahilvasilevhealth@gmail.com ) Академик редактор: Елина Балтаджиева-Трендафилова © И. Петров, З. Станков, С. Василев. Това е статия отворен достъп разпространява под условията на Creative Commons Attribution License (CC BY 4.0), която позволява използване без ограничения, разпространение, и възпроизвеждане на всякакъв носител, при условие на оригиналния автор и източник са кредитирани. Цитат:
Петров И, Станков З, Василев С (2022) Кардиогенен шок - новости и съвременни терапевтични схеми. Българска Кардиология 28(3): 7-23. https://doi.org/10.3897/bgcardio.28.e87553 |
Corresponding author: S. Vasilev ( strahilvasilevhealth@gmail.com ) Academic editor: Elina Trendafilova © I. Petrov, Z. Stankov, S. Vasilev. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation:
Petrov I, Stankov Z, Vasilev S (2022) Cardiogenic shock - novelty and emerging therapeutic concepts. Bulgarian Cardiology 28(3): 7-23. https://doi.org/10.3897/bgcardio.28.e87553 |
The cardiogenic shock is a state of low cardiac output, primarily due to cardiac dysfunction, which leads to severe organ hypoperfusion with tissue hypoxia and increased lactate levels. It presents a severe complication with a prevalence of around 15% of all forms of shock and 2-5% of the cardiogenic shock is a complications of acute heart failure. Despite the diverse etiology of the cardiogenic shock, up to 80% of the cases are due to acute myocardial infarction. The ischemia, leads to dysfunction of the myocardium cells, which causes a decline in the blood pressure and subsequent tissue hypoperfusion. The most important part is to start the treatment regime as soon as possible in the pre-shock stage. The treatment of refractory cardiogenic shock is complex, as it contains an intravenous therapy with inotropes/vasopressors and mechanical circulatory support (MCS). The MCS devices are supposed to reduce the workload of the heart and the oxygen need of the myocardial cells and in the same time to maintain an adequate coronary and systemic perfusion. There are different MCS devices like IABP, Impella, Tandem Heart, V-A ECMO. The aim of this review article is to present the new trends in the treatment approach to cardiogenic shock and to bring clarity in the treatment regimes, based on the latest studies and guidelines.