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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">97</journal-id>
      <journal-id journal-id-type="index">urn:lsid:arphahub.com:pub:B5033382-9D21-53CE-B630-B4E3A1146D51</journal-id>
      <journal-title-group>
        <journal-title xml:lang="en">Bulgarian Cardiology</journal-title>
        <abbrev-journal-title xml:lang="en">Bulgarian Cardiology</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">1310-7488</issn>
      <issn pub-type="epub">2683-1015</issn>
      <publisher>
        <publisher-name>Bulgarian Society of Cardiology</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.3897/bgcardio.28.e82418</article-id>
      <article-id pub-id-type="publisher-id">82418</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review Article</subject>
        </subj-group>
        <subj-group subj-group-type="scientific_subject">
          <subject>Endovascular Treatment (Ендоваскуларно лечение)</subject>
          <subject>Interventional Cardiology (интервенционална кардиология)</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>TAVI in bicuspid aortic valve</article-title>
      </title-group>
      <contrib-group content-type="authors">
        <contrib contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Dimitrova</surname>
            <given-names>I.N.</given-names>
          </name>
          <email xlink:type="simple">dimytrova@yahoo.com</email>
          <uri content-type="orcid">https://orcid.org/0000-0001-6198-7134</uri>
          <xref ref-type="aff" rid="A1">1</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Jorgova</surname>
            <given-names>J.</given-names>
          </name>
          <xref ref-type="aff" rid="A1">1</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Simeonov</surname>
            <given-names>P.</given-names>
          </name>
          <uri content-type="orcid">https://orcid.org/0000-0003-1882-625X</uri>
          <xref ref-type="aff" rid="A1">1</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Angelov</surname>
            <given-names>H.</given-names>
          </name>
          <xref ref-type="aff" rid="A1">1</xref>
        </contrib>
        <contrib contrib-type="author" corresp="no">
          <name name-style="western">
            <surname>Trendafilova</surname>
            <given-names>D.</given-names>
          </name>
          <xref ref-type="aff" rid="A1">1</xref>
        </contrib>
      </contrib-group>
      <aff id="A1">
        <label>1</label>
        <addr-line content-type="verbatim">University Hospital “St. Ekaterina”, Sofia, Bulgaria</addr-line>
        <institution>University Hospital “St. Ekaterina”</institution>
        <addr-line content-type="city">Sofia</addr-line>
        <country>Bulgaria</country>
      </aff>
      <author-notes>
        <fn fn-type="corresp">
          <p>Corresponding author: I.N. Dimitrova (<email xlink:type="simple">dimytrova@yahoo.com</email>).</p>
        </fn>
        <fn fn-type="edited-by">
          <p>Academic editor: В. Вълков</p>
        </fn>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2022</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>20</day>
        <month>06</month>
        <year>2022</year>
      </pub-date>
      <volume>28</volume>
      <issue>2</issue>
      <fpage>7</fpage>
      <lpage>18</lpage>
      <uri content-type="arpha" xlink:href="http://openbiodiv.net/96F62B77-0719-5F0E-BCF8-2023A879102F">96F62B77-0719-5F0E-BCF8-2023A879102F</uri>
      <history>
        <date date-type="received">
          <day>17</day>
          <month>02</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>25</day>
          <month>03</month>
          <year>2022</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>I.N. Dimitrova, J. Jorgova, P. Simeonov, H. Angelov, D. Trendafilova</copyright-statement>
        <license license-type="creative-commons-attribution" xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <abstract>
        <label>Abstract</label>
        <p>Transcatheter aortic valve implantation (TAVI) is an established choice for the treatment of severe aortic stenosis (AS) in patients who are deemed inoperable or at high surgical risk. There are limited data for the safety and effi cacy of the method in patients with bicuspid aortic valve (BAV), the most common congenital valve defect. Patients with BAV were excluded from randomized clinical trials (RCTs), comparing TAVI to surgery due to the heterogeneous anatomy of this nosological unit and concerns about unsatisfactory procedural and clinical outcomes after TAVI. With the improvement of the design of the new generations devices, with the growing technical experience of the teams and the progress in the imaging techniques, better results and fewer complications are observed, which could be a prerequisite for expanding the indications for TAVI in patients with BAV. This review presents TAVI treatment options for patients with BAV, the results of available registers in terms of safety and effi cacy of the procedure, and future perspectives.</p>
      </abstract>
    </article-meta>
  </front>
</article>
