The coronary heart disease is one of the leading causes for sudden cardiac death, cardiovascular morbidity and disability. The main risk factors, such as diabetes mellitus, arterial hypertension, dyslipidaemia, have been extensively studied and researched to this day. In the background, however, are some of the most common endocrinological diseases and abnormalities, mainly those related to thyroid hormones. The purpose of this review is to look at the role of thyroid pathology and hormones in the development of coronary heart disease, as well as their place as a prognostic marker in acute coronary syndrome.